Based on the reactions to articles posted here about gene editing, it sounds like a lot of people are skeptical about our ability to control polygenic traits like intelligence, height, and strength within the coming decades, but I'm wondering if organic biology – either due to its complexity or due to the many factors that are either random or even quantum/non-deterministic – might never be fully controllable, even by a superintelligence. I don't expect humans to still die at 80-100 years in 3024 as we do in 2024, but I don't think it can be ruled out that many aspects of medicine and biology are beyond the reach of conventional science in the same way that faster-than-light travel or entropy reversal are beyond the reach of conventional science.